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Orcabiosystems·Sacramento, CA·On-site
Manager / Senior Manager, Human Resources, Manufacturing
full time·Posted May 28, 2026
Job description
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
We have built a state-of-the-art, 100,000-square-foot manufacturing facility in Sacramento, CA (7910 Metro Air Pkwy) to ensure the consistent and reliable delivery of our high-precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life-saving therapies.
Position Summary: the Manager / Senior Manager, Human Resources (depending on experience) partners with leaders to operationalize People Team initiatives. Reporting into the People Partner, Manufacturing Site Operations, you will serve as the primary HR business partner to front-line and mid-level managers, providing strategic guidance, coaching, and day-to-day support to strengthen leadership capability, drive effective people management practices, support talent acquisition and career development initiatives, foster a positive and inclusive culture, ensure compliance, and promote operational excellence across manufacturing sites.
Key Responsibilities
Required Qualifications
- Bachelor’s degree required.
- 6 to 8+ years of progressive HR generalist experience with HRBP duties in life sciences, biotech and/or other highly regulated manufacturing environment, supporting a largely hourly workforce.
- Proactive problem-solving, time management and continuous improvement mindset.
- Demonstrated HRBP experience in training and coaching managers and supervisors in performance management, labor management, and time and attendance.
- Experience in wage and hour compliance.
- Experience with HCM/HRIS systems (e.g., Workday, ADP, Dayforce) particularly in time and attendance, scheduling, labor allocation, HR dashboards and reporting, performance management, document management, and learning & development.
- Employee relations and investigation experience.
- Strong interpersonal, coaching, and influencing skills with a high level of discretion and professionalism.
- Ability to support varying shifts as needed across multiple manufacturing sites.
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