Orcabiosystems·Sacramento, CA·On-site

Associate Director, Procurement & Materials

full time·8-10 yrs exp·Posted Dec 17, 2025

Job description

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

We have built a state-of-the-art, 100,000-square-foot manufacturing facility in Sacramento, CA (7910 Metro Air Pkwy) to ensure the consistent and reliable delivery of our high-precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life-saving therapies.

Associate Director/Director - The Associate/Director of Procurement and Materials is responsible for leading the end-to-end procurement, inventory management, and materials master data functions in support of GMP manufacturing operations. This role ensures uninterrupted supply of raw materials, consumables, packaging components, and indirect materials by overseeing purchasing, supplier management, inventory forecasting, and inventory control processes.

The Associate Directory/Director serves as the primary operational liaison with suppliers regarding purchase orders, material availability, stock shortages, quality issues, delivery performance, and supply continuity.

Key Responsibilities

Essential Duties & Key Responsibilities:

Procurement

Lead the procurement team responsible for purchasing raw materials, consumables, packaging components, capital equipment, and indirect supplies.

Ensure timely issuance, confirmation, and follow-up of purchase orders through delivery.

Negotiate pricing, contracts, and commercial terms with suppliers in partnership with Strategic Sourcing and Legal as appropriate.

Purchase Order Management

Oversee the complete purchase order lifecycle from requisition through receipt.

Ensure purchase orders accurately reflect material specifications, quantities, pricing, and delivery requirements.

Monitor supplier acknowledgements and delivery commitments.

Escalate supplier delays and coordinate recovery plans to minimize production impact.

Maintain purchasing metrics including on-time delivery, purchase order cycle time, and supplier responsiveness.

Inventory Forecasting & Materials Planning

Lead inventory forecasting activities in partnership with Supply Chain Planning and Manufacturing.

Review demand forecasts to determine future procurement requirements.

Establish inventory targets including safety stock, reorder points, and minimum/maximum inventory levels.

Balance inventory investment while minimizing stockouts and excess inventory.

Monitor inventory health, slow-moving inventory, excess inventory, and expiration risks.

Supplier Relationship Management

Build and maintain strong strategic relationships with suppliers.

Conduct regular business reviews with key suppliers.

Monitor supplier performance using key performance indicators including:

On-time delivery

Lead time adherence

Quality performance

Identify alternate suppliers and mitigate supply risks.

Stock-Out & Supply Issue Management

Serve as the primary escalation point for supplier stock shortages and material availability issues.

Coordinate supplier recovery plans for backorders and constrained materials.

Communicate supply risks to Planning, Manufacturing, and Executive Leadership.

Supplier Quality & Delivery Performance

Partner with Quality Assurance on supplier quality issues.

Coordinate supplier investigations for nonconforming materials.

Inventory Management

Partner with Warehouse and Materials Management to maintain accurate inventory.

Review inventory accuracy, cycle count performance, and inventory reconciliation.

Minimum Qualifications

Minimum Experience, Education, Certifications, Licenses:

Associate Director

Bachelor's degree in Supply Chain, Engineering, Life Sciences, Business, or related field

8–10 years of progressive procurement, materials management, inventory management, or supply chain experience in a GMP-regulated manufacturing environment

3–5 years of people leadership

Experience with ERP systems (SAP, Oracle, NetSuite, etc.)

Experience managing procurement operations, inventory management, supplier performance, and materials management

Director

Bachelor's degree in Supply Chain, Engineering, Life Sciences, Business, or related field

10–15+ years of progressive procurement, materials management, inventory management, or supply chain experience in a GMP-regulated manufacturing environment

5+ years leading procurement and materials organizations

Demonstrated success building scalable procurement organizations and improving supplier performance, inventory health, and operational efficiency

Experience leading organizational and system improvements

Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or related fields.

Reporting Structure & Authority:

Direct reports include Procurement Manager and procurement specialist(s)

Define Supervisory responsibilities include,

Oversees the daily workflow of the department and performance to goals and deliverables

Recruits, interviews, hires, and trains new staff

Provides constructive and timely performance feedback and evaluations

Other related supervisory responsibilities as assigned

Training & Continuous Improvement:

Certification in Production and Inventory Management or Logistics, such as APICS are a plus

Preferred Qualifications

Experience with autologous or allogeneic cell therapy supply chains.

Familiarity with both clinical and commercial supply chain models.

Knowledge of manufacturing, chain of identity/custody requirements, and vein-to-vein workflows.

Personal Qualities & Physical Demands

Demonstrates strong work ethic, curiosity to learn and contribute in a fast-paced collaborative environment.

Strong interpersonal skills and ability to communicate effectively.

Ability to work in a collaborative manner.

Strong problem-solving skills.

Domestic and international travel may be required from time to time as needed (approximately 10-25%).

May require occasional lifting up to 25 lbs. and gowning into cleanroom areas.

Requires sitting, standing, working in an office environment and computer use.

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